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Illinois

Psychedelic trials in Illinois

45 registered trials has a study site in Illinois, and 6 are recruiting now.

45
Trials with a site here
6
Recruiting
31
Facilities

Open now

Recruiting in this state

TrialStatusPhaseSubstanceSites
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive DisorderNCT06793397 · Cybin IRL LimitedRecruitingPhase 3psilocybin68
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)NCT07592689 · Definium Therapeutics US, Inc.RecruitingPhase 3lsd30
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive DisorderNCT07227454 · Janssen Research & Development, LLCRecruitingPhase 3ketamine35
A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant DepressionNCT07716098 · Janssen Research & Development, LLCRecruitingPhase 3ketamine4
Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSDNCT06608277 · Northwestern UniversityRecruitingPhase 2ketamine3
Cognitive Training as an Adjunct to Ketamine in Real-world ClinicsNCT06526078 · University of PittsburghRecruitingNot applicableketamine3

Facilities

Where the research happens in Illinois

FacilityCityTrials
University of ChicagoChicago12
Rush University Medical CenterChicago5
Uptown Research InstituteChicago4
Great Lakes Clinical TrialsChicago3
Rush UniversityChicago2
Psychiatric Medicine Associates LLCSkokie2
Uptown Research Institute, LLCChicago2
Neuroscience Research InstituteWinfield2
Matthew BonaChicago2
Endeavor Health Evanston HospitalEvanston1
Anesthesiology Pain Medicine CenterChicago1
University of Illinois at ChicagoChicago1
Northwestern UniversityChicago1
Chicago Research CenterChicago1
Joliet Center for Clinical ResearchJoliet1
Pillar Clinical Research, LLCLincolnwood1
Chicago CentreChicago1
Edward Hines Jr. VA Hospital, Hines, ILHines1
Great Lakes Clinical Trials, DBA Flourish ResearchChicago1
Psychiatric Medicine Associates, LLCSkokie1
Psychiatric Medicine AssociatesSkokie1
Uptown Research Institute (URI), LLCChicago1
Alexian Behavioral Health HospitalHoffman Estates1
Memorial Medical CenterSpringfield1
Clinical Site 127Chicago1
Clinical Site 120Elgin1
Uptown ResearchChicago1
Seelos Investigational SiteSpringfield1
Novartis Investigative SiteSkokie1
Stella CenterWestmont1
The Neuroscience CenterDeerfield1

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All trials

Every trial with a Illinois site

TrialStatusPhaseSubstanceSites
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive DisorderNCT06793397 · Cybin IRL LimitedRecruitingPhase 3psilocybin68
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)NCT07592689 · Definium Therapeutics US, Inc.RecruitingPhase 3lsd30
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive DisorderNCT07227454 · Janssen Research & Development, LLCRecruitingPhase 3ketamine35
A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant DepressionNCT07716098 · Janssen Research & Development, LLCRecruitingPhase 3ketamine4
Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSDNCT06608277 · Northwestern UniversityRecruitingPhase 2ketamine3
Cognitive Training as an Adjunct to Ketamine in Real-world ClinicsNCT06526078 · University of PittsburghRecruitingNot applicableketamine3
Postpartum Perineal Pain After Obstetric Anal Sphincter InjuriesNCT03470675 · Northwestern UniversityCompletedPhase 4ketamine1
A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant DepressionNCT04599855 · Janssen Research & Development, LLCCompletedPhase 4ketamine54
A Retrospective Effectiveness Trial of Ketamine-Assisted Psychotherapy in Adult Patients Coping With Mental HealthNCT05604794 · Field Trip HealthCompletedPhase 4ketamine11
VA Aripiprazole vs Esketamine for Treatment Resistant DepressionNCT05554627 · VA Office of Research and DevelopmentWithdrawnPhase 4ketamine26
A Study of Brexpiprazole Plus Ketamine in Treatment-Resistant Depression (TRD)NCT03149991 · Massachusetts General HospitalCompletedPhase 4ketamine6
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"NCT06564818 · Cybin IRL LimitedActive, not recruitingPhase 3psilocybin45
Efficacy, Safety, and Tolerability of COMP360 in Participants With TRDNCT05624268 · COMPASS PathwaysCompletedPhase 3psilocybin40
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRDNCT05711940 · COMPASS PathwaysActive, not recruitingPhase 3psilocybin116
A Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)NCT06941844 · Definium Therapeutics US, Inc.Active, not recruitingPhase 3lsd22
Psilocybin for Major Depressive Disorder (MDD)NCT06308653 · Usona InstituteActive, not recruitingPhase 3psilocybin29
A Phase 3 Trial of DT120 for Generalized Anxiety Disorder (Voyage)NCT06741228 · Definium Therapeutics US, Inc.Active, not recruitingPhase 3lsd34
A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionNCT02417064 · Janssen Research & Development, LLCCompletedPhase 3ketamine90
A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionNCT02418585 · Janssen Research & Development, LLCCompletedPhase 3ketamine48
A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant DepressionNCT02493868 · Janssen Research & Development, LLCCompletedPhase 3ketamine155
A Long-term Safety Study of Esketamine Nasal Spray in Treatment-resistant DepressionNCT02782104 · Janssen Research & Development, LLCCompletedPhase 3ketamine173
54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for SuicideNCT03039192 · Janssen Research & Development, LLCCompletedPhase 3ketamine56
54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for SuicideNCT03097133 · Janssen Research & Development, LLCCompletedPhase 3ketamine61
A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants With Generalized Anxiety Disorder (GAD)NCT06051721 · Cybin IRL LimitedCompletedPhase 2dmt6
A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive DisorderNCT06340958 · Clexio Biosciences Ltd.CompletedPhase 2ketamine23
A Study of Psilocybin for Major Depressive Disorder (MDD)NCT03866174 · Usona InstituteCompletedPhase 2psilocybin11
A Dose-Finding Study of MM120 (LSD D-Tartrate) for the Treatment of Anxiety SymptomsNCT05407064 · Definium Therapeutics US, Inc.CompletedPhase 2lsd22
Psilocybin in Co-occuring Major Depressive Disorder and Borderline Personality DisorderNCT05399498 · University of ChicagoCompletedPhase 2psilocybin1
A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant DepressionNCT01998958 · Janssen Research & Development, LLCCompletedPhase 2ketamine25
Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for SuicideNCT03185819 · Janssen Research & Development, LLCCompletedPhase 2ketamine51
A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of SuicideNCT04669665 · Seelos Therapeutics, Inc.CompletedPhase 2ketamine21
Proof of Concept Study Evaluating the Efficacy and Safety of MIJ821 in Patients With Treatment-resistant DepressionNCT03756129 · Novartis PharmaceuticalsCompletedPhase 2ketamine12
A Study to Assess Feasibility of Using Clinician-directed and Digital Application Supported Cognitive Behavior Therapy (CBT) in Conjunction With Esketamine in Participants With Treatment-resistant DepressionNCT05268497 · Janssen Research & Development, LLCWithdrawnPhase 1ketamine5
Mood Effects of Serotonin AgonistsNCT03790358 · University of ChicagoCompletedPhase 1lsd2
Effect of Stimulant Drugs on Social PerceptionNCT03790618 · University of ChicagoCompletedPhase 1mdma1
Mood Effects of Serotonin Agonists ExtendedNCT03934710 · University of ChicagoCompletedPhase 1lsd1
Mood Effects of Serotonin Agonists: DepressionNCT07017478 · University of ChicagoCompletedEarly Phase 1lsd1
Drug Effects on Mood and Behavior - ExpectancyNCT07061886 · University of ChicagoCompletedEarly Phase 1lsd1
Effects of Drugs on Responses to Brain and Emotional ProcessesNCT04053036 · University of ChicagoCompletedEarly Phase 1mdma1
Prosocial Effects of MDMANCT05948683 · University of ChicagoCompletedEarly Phase 1mdma1
Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social FunctionNCT05379959 · University of ChicagoCompletedEarly Phase 1mdma1
Drug Effects on Interpersonal InteractionNCT05123716 · University of ChicagoCompletedEarly Phase 1mdma1
Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces CohortNCT05855876 · Stella CenterUnknown statusN/Aketamine1
Effects of MDMA on Social and Emotional ProcessingNCT01849419 · University of ChicagoCompletedNot applicablemdma1
Neuromodulation to Facilitate the Effect of KetamineNCT01816958 · The Neuroscience Center, LLCCompletedN/Aketamine1

Site locations from ClinicalTrials.gov API v2, data build 2026-08-25.

Elsewhere

Other states