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CompletedEarly Phase 1

Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function

NCT05379959 · MASM · University of Chicago

Closed to entry
Status
Not accepting participants
Early Phase 1
Phase
43
Target enrolment
1
Study sites
1 US states

What it is testing

Summary

To study the effects of MDMA, compared to a prototypical stimulant, on social motivation, social ability, and neural indices of social function in healthy volunteers

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • Profile of Mood States

    Measured over Time Frame: Baseline-72 hours after completion of the sessions

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years to 40 Years
Ages
All
Sex
Accepted
Healthy volunteers
Inclusion Criteria: * BMI between 19 and 30 (no one under 130 lbs) * Smokers smoking less than 25 cigarettes per week * Have used ecstasy no more than 40 times with no adverse responses. Exclusion Criteria: * High blood pressure * Any medical condition requiring regular medication * Individuals with a current (within the last year) DSM-IV Axis 1 diagnosis * Individuals with a history of dependence on stimulant drugs. * Women who are pregnant or trying to become pregnant

Where

1 study site

FacilityCityRegionCountry
University of ChicagoChicagoIllinoisUnited States

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT05379959 on ClinicalTrials.gov →

Last updated in the registry 2024-01-24. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits