Skip to content

Pennsylvania

Psychedelic trials in Pennsylvania

41 registered trials has a study site in Pennsylvania, and 7 are recruiting now.

41
Trials with a site here
7
Recruiting
26
Facilities

Open now

Recruiting in this state

Facilities

Where the research happens in Pennsylvania

FacilityCityTrials
Adams Clinical PhiladelphiaPhiladelphia5
Western Psychiatric Institute and ClinicPittsburgh4
University of PennsylvaniaPhiladelphia3
University of PittsburghPittsburgh3
Magee Womens Hospital of UPMCPittsburgh2
Flourish Research PhiladelphiaPhiladelphia1
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PAPhiladelphia1
NeuroneticsMalvern1
Loeffler BuildingPittsburgh1
Lehigh Center for Clinical ResearchAllentown1
University of Pennsylvania Medical CenterPhiladelphia1
Philadelphia MultiService Center, Philadelphia, PAPhiladelphia1
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PAPittsburgh1
UPMC Late-Life Depression, Evaluation, Prevention, and Treatment ProgramPittsburgh1
Global Medical Institutes, LLC, Scranton Medical InstituteMoosic1
Suburban Research AssociatesMedia1
Scranton Medical InstituteMoosic1
Clinical Site 106Media1
Clinical Site 118Philadelphia1
UPMC Montefiore Hospital CTRCPittsburgh1
Minhnoi C Wroble BiglanPittsburgh1
UPMC PresbyterianPittsburgh1
UPMC Shadyside HospitalPittsburgh1
Thomas Jefferson University HospitalPhiladelphia1
Apollo Neuroscience, Inc.Pittsburgh1
Drexel UniversitsyPhiladelphia1

Stay told

When a trial opens in Pennsylvania

Research alerts

Get a notification when a trial for trials in Pennsylvania starts recruiting

This registry is rebuilt every day. If no trial is recruiting for you today, that can change within weeks.

This form sends your email address and the topic of this page to Brevo, our email provider, which stores them on servers in the European Union. We never sell that address, never share it with anyone, and never use it for advertising. One email deletes it. What is held, and where.

All trials

Every trial with a Pennsylvania site

TrialStatusPhaseSubstanceSites
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive DisorderNCT06793397 · Cybin IRL LimitedRecruitingPhase 3psilocybin68
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant DepressionNCT07226232 · VA Office of Research and DevelopmentRecruitingPhase 3psilocybin5
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)NCT07592689 · Definium Therapeutics US, Inc.RecruitingPhase 3lsd30
Psilocybin on Brain Mechanisms of Motivation in OUDNCT06810310 · University of PennsylvaniaRecruitingPhase 2psilocybin1
Wellcome Leap Psilocybin for OUDNCT06786325 · Anna Rose Childress, Ph.D.RecruitingPhase 2psilocybin1
Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of KetamineNCT06788249 · University of PennsylvaniaRecruitingEarly Phase 1ketamine1
Retrospective Analyses of the Greenbrook Database Evaluating Mental Health TreatmentsNCT06997549 · NeuroneticsRecruitingN/Aketamine1
Ketamine + Cognitive Training for Suicidality in the Medical SettingNCT04578938 · Rebecca PriceActive, not recruitingPhase 4ketamine1
Anhedonia, Development, and Emotions: Phenotyping and TherapeuticsNCT05487885 · Erika ForbesCompletedPhase 4ketamine1
Comparative Effectiveness of ECT vs. KETAMINE Over the LifespanNCT06034821 · Brigham and Women's HospitalEnrolling by invitationPhase 4ketamine10
A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant DepressionNCT04599855 · Janssen Research & Development, LLCCompletedPhase 4ketamine54
Ketamine + Cognitive Training for Suicidality in the Medical Setting: PilotNCT04154150 · Rebecca PriceTerminatedPhase 4ketamine1
VA Aripiprazole vs Esketamine for Treatment Resistant DepressionNCT05554627 · VA Office of Research and DevelopmentWithdrawnPhase 4ketamine26
Ketamine for Older Adults PilotNCT04504175 · Washington University School of MedicineCompletedPhase 4ketamine5
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"NCT06564818 · Cybin IRL LimitedActive, not recruitingPhase 3psilocybin45
Efficacy, Safety, and Tolerability of COMP360 in Participants With TRDNCT05624268 · COMPASS PathwaysCompletedPhase 3psilocybin40
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRDNCT05711940 · COMPASS PathwaysActive, not recruitingPhase 3psilocybin116
A Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)NCT06941844 · Definium Therapeutics US, Inc.Active, not recruitingPhase 3lsd22
A Phase 3 Trial of DT120 for Generalized Anxiety Disorder (Voyage)NCT06741228 · Definium Therapeutics US, Inc.Active, not recruitingPhase 3lsd34
A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionNCT02417064 · Janssen Research & Development, LLCCompletedPhase 3ketamine90
A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionNCT02418585 · Janssen Research & Development, LLCCompletedPhase 3ketamine48
A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant DepressionNCT02422186 · Janssen Research & Development, LLCCompletedPhase 3ketamine69
A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant DepressionNCT02493868 · Janssen Research & Development, LLCCompletedPhase 3ketamine155
A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant DepressionNCT02497287 · Janssen Research & Development, LLCCompletedPhase 3ketamine109
A Long-term Safety Study of Esketamine Nasal Spray in Treatment-resistant DepressionNCT02782104 · Janssen Research & Development, LLCCompletedPhase 3ketamine173
A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO StudyNCT04103892 · Clexio Biosciences Ltd.CompletedPhase 2ketamine46
A Study of Ketamine in Patients With Treatment-resistant DepressionNCT01627782 · Janssen Research & Development, LLCCompletedPhase 2ketamine13
A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant DepressionNCT01998958 · Janssen Research & Development, LLCCompletedPhase 2ketamine25
A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for SuicideNCT02133001 · Janssen Research & Development, LLCCompletedPhase 2ketamine14
Repeated Neurocognitive Measurements in Depressed PatientsNCT04916548 · Rebecca PriceCompletedPhase 1 / Phase 2ketamine1
Ketamine + Mindfulness for DepressionNCT05168735 · Rebecca PriceCompletedPhase 1 / Phase 2ketamine1
Intravenous Ketamine Plus Neurocognitive Training for DepressionNCT03237286 · Rebecca PriceCompletedPhase 1 / Phase 2ketamine1
Ketamine to Improve Recovery After Cesarean Delivery - Part 1NCT04037085 · Grace Lim, MD, MSCompletedPhase 2ketamine2
Psilocybin After Trauma Surgery for PainNCT07406828 · Trent EmerickNot yet recruitingPhase 1psilocybin1
Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean DeliveryNCT06767566 · University of UtahSuspendedPhase 1ketamine1
Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1)NCT05907213 · Grace Lim, MD, MSCompletedPhase 1ketamine1
Transition From Acute to Chronic Opioid Use and Chronic PainNCT07211399 · Jacques E. ChellyWithdrawnEarly Phase 1ketamine1
Ketamine for Refractory Chronic Migraine: a Pilot StudyNCT03896256 · Thomas Jefferson UniversityCompletedEarly Phase 1ketamine1
Testing the Effectiveness of Cognitive Training Among Depressed Patients Receiving Esketamine TreatmentNCT05719909 · University of PittsburghSuspendedNot applicableketamine1
Sustaining Remission From PTSD Using Tuned Vibroacoustic Stimulation (TVS) Following MDMA-Assisted PsychotherapyNCT05274230 · Apollo Neuroscience, Inc.Unknown statusNot applicablemdma1
Mindfulness-based Dance/Movement Therapy for Chronic Low Back PainNCT03986489 · Drexel UniversityUnknown statusNot applicabledmt1

Site locations from ClinicalTrials.gov API v2, data build 2026-08-25.

Elsewhere

Other states