Florida

Psychedelic trials in Florida

36 registered trials has a study site in Florida, and 3 are recruiting now.

Trials with a site here

Recruiting

Facilities

Open now

Recruiting in this state

Trial	Status	Phase	Substance	Sites
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive DisorderNCT06793397 · Cybin IRL Limited	Recruiting	Phase 3	psilocybin	68
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)NCT07592689 · Definium Therapeutics US, Inc.	Recruiting	Phase 3	lsd	30
Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit PatientsNCT07639359 · Hospital Italiano de Buenos Aires	Recruiting	Phase 2	ketamine	2

Facilities

Where the research happens in Florida

Facility	City	Trials
Seelos Investigational Site	Hollywood	5
Charter Research	Orlando	3
Research Centers of America	Hollywood	3
Innovative Clinical Research, Inc.	Lauderhill	3
Segal Trials	Lauderhill	3
Clinical Neuroscience Solutions, Inc	Orlando	2
Clinical Neurosciecne Solutions, Inc. dba CNS Healthcare	Orlando	2
Clinical Neuroscience Solutions Inc.	Jacksonville	2
Clinical Site 105	Lauderhill	2
CNS Healthcare	Jacksonville	1
Accel Research Sites - Maitland	Maitland	1
Aqualane Clinical Research	Naples	1
Clinical Neuroscience Solutions, LLC (Jacksonville)	Jacksonville	1
K2 Medical Research (Maitland)	Maitland	1
Clinical Neuroscience Solutions, LLC (Orlando)	Orlando	1
K2 Medical Research (Tampa)	Tampa	1
Mayo Clinic	Jacksonville	1
Velocity Clinical Research, Hallandale Beach	Hallandale	1
Accel Research Sites	Lakeland	1
APG Research LLC	Orlando	1
USF, Department of Psychiatry and Behavioral Neurosciences	Tampa	1
Neuroscience Research Institute	West Palm Beach	1
K2 Medical Research-Maitland	Maitland	1
Floridian Neuroscience Institute	Miami	1
Segal Trials West Broward	North Miami	1
Combined Research Orlando Phase I-IV	Orlando	1
K2 Medical Research - Tampa	Tampa	1
APG Research, LLC	Orlando	1
DMI Health Care Group, Inc	Tampa	1
Meridien Research/Accel Research	Tampa	1
Central Miami Medical Institute, LLC	Miami	1
Behavioral Clinical Research, Inc.	Miami Lakes	1
Health Synergy Clinical Research	Okeechobee	1
APG Research, LLC- Advanced Psychiatric Group	Orlando	1
University South Florida	Tampa	1
Stedman Clinical Trials	Tampa	1
Health Synergy Clinical Research, LLC	West Palm Beach	1
Bradenton Research Center, Inc.	Bradenton	1
Clinical Neuroscience Solutions, Inc - Jacksonville	Jacksonville	1
Clinical Neuroscience Solutions, Inc - Orlando	Orlando	1

Stay told

When a trial opens in Florida

All trials

Every trial with a Florida site

Trial	Status	Phase	Substance	Sites
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive DisorderNCT06793397 · Cybin IRL Limited	Recruiting	Phase 3	psilocybin	68
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)NCT07592689 · Definium Therapeutics US, Inc.	Recruiting	Phase 3	lsd	30
Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit PatientsNCT07639359 · Hospital Italiano de Buenos Aires	Recruiting	Phase 2	ketamine	2
A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant DepressionNCT04599855 · Janssen Research & Development, LLC	Completed	Phase 4	ketamine	54
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"NCT06564818 · Cybin IRL Limited	Active, not recruiting	Phase 3	psilocybin	45
Efficacy, Safety, and Tolerability of COMP360 in Participants With TRDNCT05624268 · COMPASS Pathways	Completed	Phase 3	psilocybin	40
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRDNCT05711940 · COMPASS Pathways	Active, not recruiting	Phase 3	psilocybin	116
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)NCT06809595 · Definium Therapeutics US, Inc.	Active, not recruiting	Phase 3	lsd	36
A Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)NCT06941844 · Definium Therapeutics US, Inc.	Active, not recruiting	Phase 3	lsd	22
Psilocybin for Major Depressive Disorder (MDD)NCT06308653 · Usona Institute	Active, not recruiting	Phase 3	psilocybin	29
A Phase 3 Trial of DT120 for Generalized Anxiety Disorder (Voyage)NCT06741228 · Definium Therapeutics US, Inc.	Active, not recruiting	Phase 3	lsd	34
A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionNCT02417064 · Janssen Research & Development, LLC	Completed	Phase 3	ketamine	90
A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionNCT02418585 · Janssen Research & Development, LLC	Completed	Phase 3	ketamine	48
A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant DepressionNCT02422186 · Janssen Research & Development, LLC	Completed	Phase 3	ketamine	69
A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant DepressionNCT02493868 · Janssen Research & Development, LLC	Completed	Phase 3	ketamine	155
A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant DepressionNCT02497287 · Janssen Research & Development, LLC	Completed	Phase 3	ketamine	109
A Long-term Safety Study of Esketamine Nasal Spray in Treatment-resistant DepressionNCT02782104 · Janssen Research & Development, LLC	Completed	Phase 3	ketamine	173
54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for SuicideNCT03097133 · Janssen Research & Development, LLC	Completed	Phase 3	ketamine	61
NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar DepressionNCT03396601 · NeuroRx, Inc.	Unknown status	Phase 3	ketamine	2
A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants With Generalized Anxiety Disorder (GAD)NCT06051721 · Cybin IRL Limited	Completed	Phase 2	dmt	6
A Study of Ketamine Infusions to Treat Clinically-depressed ICU PatientsNCT05803551 · Mayo Clinic	Terminated	Phase 2	ketamine	1
A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive DisorderNCT06340958 · Clexio Biosciences Ltd.	Completed	Phase 2	ketamine	23
Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002NCT06816433 · Global Coalition for Adaptive Research	Suspended	Phase 2	ketamine	9
A Study of Psilocybin for Major Depressive Disorder (MDD)NCT03866174 · Usona Institute	Completed	Phase 2	psilocybin	11
A Dose-Finding Study of MM120 (LSD D-Tartrate) for the Treatment of Anxiety SymptomsNCT05407064 · Definium Therapeutics US, Inc.	Completed	Phase 2	lsd	22
A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO StudyNCT04103892 · Clexio Biosciences Ltd.	Completed	Phase 2	ketamine	46
A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive DisorderNCT05733546 · COMPASS Pathways	Active, not recruiting	Phase 2	psilocybin	5
A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant DepressionNCT01998958 · Janssen Research & Development, LLC	Completed	Phase 2	ketamine	25
Evaluation of Psilocybin (TRP-8802) in the Treatment of Binge Eating DisorderNCT05035927 · TRYP Therapeutics	Completed	Phase 2	psilocybin	1
A Randomized, Placebo-Controlled, Double-Blind Study to Assess Safety and Efficacy of PCN-101 in TRDNCT05414422 · Perception Neuroscience	Completed	Phase 2	ketamine	21
Psilocybin-Assisted Psychotherapy for Anxiety in People With Stage IV MelanomaNCT00979693 · Multidisciplinary Association for Psychedelic Studies	Withdrawn	Phase 2	psilocybin	1
A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of SuicideNCT04669665 · Seelos Therapeutics, Inc.	Completed	Phase 2	ketamine	21
Proof of Concept Study Evaluating the Efficacy and Safety of MIJ821 in Patients With Treatment-resistant DepressionNCT03756129 · Novartis Pharmaceuticals	Completed	Phase 2	ketamine	12
Sequential Therapy for the Treatment of Severe Bipolar Depression.NCT02974010 · NeuroRx, Inc.	Completed	Phase 2	ketamine	4
Pharmacokinetics and Safety of GH001 Delivered Via a GH001 Aerosol Delivery System in Healthy SubjectsNCT07540494 · GH Research Ireland Limited	Not yet recruiting	Phase 1	dmt	1
PSIL201 Long-term Follow-up Study: Psilocybin or Niacin / Major Depressive DisorderNCT04353921 · Usona Institute	Terminated	N/A	psilocybin	1

Site locations from ClinicalTrials.gov API v2, data build 2026-08-25.

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