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CompletedPhase 1

Mood Effects of Serotonin Agonists

NCT03790358 · University of Chicago

Closed to entry
Status
Not accepting participants
Phase 1
Phase
80
Target enrolment
2
Study sites
1 US states

What it is testing

Summary

The purpose of this study is to determine the effects of very low doses of serotonergic agonists on depressed mood in human volunteers.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • Change From Baseline in Profile of Mood States (POMS)

    Measured over End of study (Baseline - time 0 and approximately 8 weeks later)

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years to 35 Years
Ages
All
Sex
Accepted
Healthy volunteers
Inclusion Criteria: * English fluency * High school level education * BMI between 19 and 30 Exclusion Criteria: * Diagnosed medical condition * women who are nursing, pregnant, or plan to become pregnant within 3 months * History of psychotic disorder or family history of psychotic disorder

Where

2 study sites

FacilityCityRegionCountry
Matthew BonaChicagoIllinoisUnited States
University of ChicagoChicagoIllinoisUnited States

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT03790358 on ClinicalTrials.gov →

Last updated in the registry 2024-01-24. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits