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Indication

Alcohol Use Disorder

30 registered trials testing LSD, Psilocybin, MDMA, Ketamine, DMT for this indication, 11 recruiting now.

Sponsors register this under 2 different names, all collected here: Alcohol Use Disorder · Alcohol Use Disorder (AUD)

30
Registered trials
11
Recruiting
2
In Phase 3

Substances tested

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Get a notification when a trial for Alcohol Use Disorder trials starts recruiting

This registry is rebuilt every day. If no trial is recruiting for you today, that can change within weeks.

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Trials

All 30 trials for Alcohol Use Disorder

TrialStatusPhaseSubstanceSites
Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive SymptomsNCT07638553 · Centre Hospitalier Universitaire de NīmesRecruitingPhase 3psilocybin8
MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use DisorderNCT07118839 · VA Office of Research and DevelopmentRecruitingPhase 2 / Phase 3mdma2
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUDNCT06349083 · NYU Langone HealthRecruitingPhase 2psilocybin1
Ketamine for Combined Depression and Alcohol Use DisorderNCT06090422 · University Hospital of North NorwayRecruitingPhase 1 / Phase 2ketamine1
LSD Treatment for Persons With Alcohol Use DisorderNCT05474989 · Felix MuellerRecruitingPhase 2lsd2
Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use DisorderNCT06969937 · Dr. med. Marcus HerdenerRecruitingPhase 2ketamine1
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator TrialNCT06405607 · University of IowaRecruitingPhase 2psilocybin, ketamine1
MDMA for AUD/PTSD ComorbidityNCT05943665 · Carolina L Haass-KofflerRecruitingPhase 2mdma1
Psilocybin-Assisted Psychotherapy for Alcohol Use DisorderNCT05995769 · University of CalgaryRecruitingPhase 2psilocybin1
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)NCT06070649 · Yale UniversityRecruitingPhase 1dmt1
ACT_for Alcohol Use Disorder and DepressionNCT06620276 · Centre hospitalier de l'Université de Montréal (CHUM)RecruitingNot applicableketamine1
PsiloStudy: Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)NCT06853912 · Nathan Brashares SackettActive, not recruitingPhase 2psilocybin1
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use DisorderNCT07296094 · Brigham and Women's HospitalNot yet recruitingPhase 2psilocybin1
Psilocybin-assisted Therapy for Treatment of Alcohol Use DisorderNCT05416229 · Anders Fink-Jensen, MD, DMSciCompletedPhase 2psilocybin1
Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use DisorderNCT04620759 · Johns Hopkins UniversityActive, not recruitingPhase 2psilocybin1
Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use DisorderNCT07405606 · Centre for Addiction and Mental HealthNot yet recruitingPhase 2psilocybin1
Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL)NCT07247370 · South West Sydney Local Health DistrictNot yet recruitingPhase 1 / Phase 2ketamine1
Psilocybin-Assisted vs Ketamine-Assisted Psychotherapy for Alcohol Use DisorderNCT05421065 · Peggy C NopoulosActive, not recruitingPhase 2psilocybin, ketamine1
Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use DisorderNCT02461927 · VA Office of Research and DevelopmentCompletedPhase 1 / Phase 2ketamine1
Ketamine for the Treatment for Alcohol Use Disorder in the EDNCT05661669 · Brigham and Women's HospitalWithdrawnPhase 2ketamine1
Psilocybin-Assisted Psychotherapy in Adults With Alcohol Use Disorder (AUD)NCT05646303 · Clairvoyant TherapeuticsUnknown statusPhase 2psilocybin12
Psilocybin for Treatment of Alcohol Use Disorder: a Feasibility StudyNCT04718792 · Anders Fink-Jensen, MD, DMSciUnknown statusPhase 2psilocybin1
Psilocybin-assisted Therapy for Alcohol Use DisorderNCT06444243 · University of SydneyUnknown statusPhase 2psilocybin—
MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress DisorderNCT05709353 · University of SydneyUnknown statusPhase 2mdma2
Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted PatientsNCT04141501 · University of ZurichCompletedPhase 2psilocybin1
Pilot Trial of Visual Healing® in Psilocybin-assisted Therapy for Alcohol Use DisorderNCT04410913 · Keith HeinzerlingActive, not recruitingPhase 2psilocybin1
Naltrexone Plus Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use DisorderNCT03658330 · VA Connecticut Healthcare SystemCompletedPhase 2ketamine—
Bristol Imperial MDMA in Alcoholism StudyNCT04158778 · Imperial College LondonUnknown statusPhase 1mdma1
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic PsychedelicsNCT06624137 · Yale UniversityTerminatedN/Alsd, psilocybin, dmt2
Observational Pilot Study to Explore the Social and Health Impacts of a New Model of Care in Oregon: Psilocybin Services on AlcoholismNCT07189988 · Healing Advocacy FundActive, not recruitingN/Apsilocybin1

Records from ClinicalTrials.gov API v2, data build 2026-08-25. Indications are the sponsors’ own words. LSD.com reports registered clinical research. It is not medical advice, it is not a recommendation to take any substance, and trial listings are not endorsements. Talk to a clinician.