Indication

Suicidal Ideation

36 registered trials testing Psilocybin, Ketamine, DMT, Ibogaine for this indication, 5 recruiting now.

Registered trials

Recruiting

In Phase 3

Substances tested

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When a new trial opens

Trials

All 36 trials for Suicidal Ideation

Trial	Status	Phase	Substance	Sites
Understanding and Treating Suicidal Ideation With KetamineNCT06891300 · The Royal's Institute of Mental Health Research	Recruiting	Phase 2 / Phase 3	ketamine	1
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)NCT07569198 · Joshua Rosenblat	Recruiting	Phase 2	ketamine	1
Inhaled DMT for Major Depressive DisorderNCT07562191 · Universidade Federal do Rio Grande do Norte	Recruiting	Phase 2	dmt	5
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal EffectsNCT05786066 · Yale University	Recruiting	Phase 2	ketamine	1
Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency DepartmentNCT06085937 · Lindsay Maguire, MD	Recruiting	Phase 1	ketamine	2
IM Ketamine vs Midazolam for Suicidal ER PatientsNCT04640636 · New York State Psychiatric Institute	Suspended	Phase 4	ketamine	1
Effectiveness of Ketamine for Depression and Suicidal Ideation in the Emergency DepartmentNCT04266288 · MercyOne Des Moines Medical Center	Completed	Phase 4	ketamine	1
The Effect of Ketamine on the Length of Hospital Stay of Patients Hospitalized With Suicidal Ideation.NCT02997722 · Allen Richert	Terminated	Phase 4	ketamine	1
Ketamine in the Treatment of Suicidal DepressionNCT01700829 · New York State Psychiatric Institute	Completed	Phase 4	ketamine	1
Intranasal Ketamine for Late-Life Depression and Suicidal IdeationNCT02295787 · Massachusetts General Hospital	Withdrawn	Phase 4	ketamine	—
Ketamine For Suicidal IdeationNCT01507181 · James Murrough	Completed	Phase 4	ketamine	1
Effects of Ketamine in the Acute Phase of Suicidal IdeationNCT02299440 · Centre Hospitalier Universitaire de Nīmes	Completed	Phase 3	ketamine	9
NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar DepressionNCT03396601 · NeuroRx, Inc.	Unknown status	Phase 3	ketamine	2
Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol AbuseNCT03539887 · The University of Texas Health Science Center, Houston	Completed	Phase 3	ketamine	1
Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal IdeationNCT05468840 · University of Ottawa	Unknown status	Phase 3	ketamine	1
The Effect of Ketamine on Mechanises Underlying Suicidal Ideation and Drug-resistant Major DepressionNCT02037503 · Tel-Aviv Sourasky Medical Center	Unknown status	Phase 3	ketamine	1
The Impact of Ketamine on the Reward Circuitry of Suicidal PatientsNCT02532153 · Massachusetts General Hospital	Withdrawn	Phase 3	ketamine	1
Emergency Ketamine Treatment of Suicidal IdeationNCT02183272 · University of Cincinnati	Unknown status	Phase 2 / Phase 3	ketamine	1
Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic TherapiesNCT07484906 · University of New Mexico	Withdrawn	Phase 2	psilocybin	—
The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal IdeationNCT05220410 · Sheppard Pratt Health System	Completed	Phase 2	psilocybin	1
Ketamine for OUD and Suicidal Ideation in the EDNCT06111339 · Brigham and Women's Hospital	Terminated	Phase 2	ketamine	1
Ketamine Infusion for Rapid Reduction of Suicidality in PediatricsNCT04955470 · University of British Columbia	Terminated	Phase 1 / Phase 2	ketamine	1
Intramuscular Ketamine for Suicidal IdeationNCT05105061 · Icahn School of Medicine at Mount Sinai	Withdrawn	Phase 2	ketamine	1
Sequential Therapy for the Treatment of Severe Bipolar Depression.NCT02974010 · NeuroRx, Inc.	Completed	Phase 2	ketamine	4
A Single Ketamine Infusion Combined With Music for Suicidal IdeationNCT04658420 · The University of Texas Health Science Center at Tyler	Unknown status	Phase 2	ketamine	1
Ketamine for Suicidality in Bipolar DepressionNCT01944293 · New York State Psychiatric Institute	Completed	Phase 1 / Phase 2	ketamine	1
ED Treatment of Suicidal Patients With Ketamine InfusionNCT03502551 · University of California, Davis	Withdrawn	Phase 2	ketamine	1
Intranasal Ketamine for Suicidal Ideation in VeteransNCT03788694 · Bronx Veterans Medical Research Foundation, Inc	Withdrawn	Early Phase 1	ketamine	1
Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency DepartmentNCT05217706 · Rady Children's Hospital, San Diego	Unknown status	Early Phase 1	ketamine	1
Ketamine for Mood Disorders With Suicidal IdeationNCT04099771 · The Miriam Hospital	Unknown status	Early Phase 1	ketamine	1
Effect of Ketamine vs. Active Placebo on Suicidal Ideation in Depressed Inpatients With Major Depressive Disorder or Bipolar Depression.NCT02593643 · Sunnybrook Health Sciences Centre	Completed	Early Phase 1	ketamine	1
Trifecta Research StudyNCT07717866 · Axial Therapeutic Research	Active, not recruiting	N/A	dmt, ibogaine	1
Psychotherapy Combined With Intranasal Esketamine for the Treatment of Suicidal IdeationNCT07396220 · University of California, San Diego	Enrolling by invitation	Not applicable	ketamine	1
Esketamine vs ECT for Acute SuicidalityNCT06355180 · Capital Medical University	Completed	Not applicable	ketamine	6
Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal IdeationNCT06366334 · Children's Hospital of Eastern Ontario	Unknown status	Not applicable	ketamine	1
Treatment of Suicidal Ideation With Intravenous Ketamine InfusionNCT01887990 · University of Alabama at Birmingham	Completed	Not applicable	ketamine	1

Records from ClinicalTrials.gov API v2, data build 2026-08-25. Indications are the sponsors’ own words. LSD.com reports registered clinical research. It is not medical advice, it is not a recommendation to take any substance, and trial listings are not endorsements. Talk to a clinician.