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Indication

Depressive Symptoms

11 registered trials testing Psilocybin, Ketamine for this indication, 1 recruiting now.

11
Registered trials
1
Recruiting
1
In Phase 3

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This registry is rebuilt every day. If no trial is recruiting for you today, that can change within weeks.

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Trials

All 11 trials for Depressive Symptoms

TrialStatusPhaseSubstanceSites
Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's DiseaseNCT04123314 · Johns Hopkins UniversityRecruitingEarly Phase 1psilocybin1
Dexmedetomidine-Esketamine Combination on Depression and Anxiety After Laparoscopic Ureteral ReconstructionNCT07753772 · Peking University First HospitalNot yet recruitingPhase 4ketamine1
Intranasal Esketamine-dexmedetomidine Combination and Postpartum DepressionNCT07639099 · Peking University First HospitalNot yet recruitingPhase 4ketamine1
Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for DepressionNCT05615948 · Theresa Jacob, PhD, MPHCompletedPhase 4ketamine1
Dexamethasone and Ketamine on Change of Postoperative MoodNCT03194594 · Wonkwang University HospitalCompletedPhase 4ketamine1
Effect of Subanesthetic Dose of Ketamine Combined With Propofol on Cognitive Function in Depressive Patients Undergoing Electroconvulsive TherapyNCT02305394 · First Affiliated Hospital of Chongqing Medical UniversityUnknown statusPhase 4ketamine1
Esketamine and Perioperative Depressive SymptomsNCT04425473 · Beijing Tiantan HospitalCompletedPhase 2 / Phase 3ketamine1
Electrophysiologic Mechanisms of Ketamine Antidepressant ResponseNCT07768618 · Emory UniversityNot yet recruitingPhase 2ketamine1
Psychopharmacology of Psilocybin in Cancer PatientsNCT00465595 · Johns Hopkins UniversityCompletedPhase 2psilocybin1
Ketamine-Assisted PsychoTherapy ViAbility in Treating Cancer-related Emotional DistressNCT05344625 · Northwell HealthWithdrawnEarly Phase 1ketamine—
Effect of Esketamine on Depressive Symptoms of Obese Patients Undergoing Laparoscopic Sleeve GastrectomyNCT06199011 · The Second Hospital of Anhui Medical UniversityUnknown statusNot applicableketamine—

Records from ClinicalTrials.gov API v2, data build 2026-08-25. Indications are the sponsors’ own words. LSD.com reports registered clinical research. It is not medical advice, it is not a recommendation to take any substance, and trial listings are not endorsements. Talk to a clinician.