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CompletedPhase 2

Understanding How Ketamine Brings About Rapid Improvement in OCD

NCT02624596 · MKET · Stanford University

Closed to entry
Status
Not accepting participants
Phase 2
Phase
120
Target enrolment
1
Study sites
1 US states

What it is testing

Summary

The purpose of this study is to understand how ketamine brings about rapid improvement in Obsessive-Compulsive Disorder (OCD) symptoms.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • improvement in the severity of OCD symptoms as measured by the Yale-Brown Obsessive Compulsive Scale (YBOCS)

    Measured over Up to 6 months

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years to 65 Years
Ages
All
Sex
Accepted
Healthy volunteers
Inclusion Criteria for participants with OCD: * age 18-65 * Primary diagnosis of OCD * Sufficient severity of OCD symptoms * ability to tolerate a treatment-free period * capacity to provide informed consent Inclusion criteria for healthy controls: * ages 18-65 * capacity to provide informed consent Exclusion criteria for participants with OCD: * Psychiatric or medical conditions that make participation unsafe * pregnant or nursing females * concurrent use of any medications that might increase the risk of participation (e.g. drug interactions) * presence of metallic device or dental braces Exclusion criteria for healthy controls: * any current or lifetime psychiatric diagnosis * pregnant or nursing females * major medical or neurological problem * presence of metallic device or dental braces

Where

1 study site

FacilityCityRegionCountry
Stanford UniversityStanfordCaliforniaUnited States

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT02624596 on ClinicalTrials.gov →

Last updated in the registry 2026-08-13. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits

Substance

Recruiting in

All 10 trials from Stanford University →