Not yet recruitingPhase 3

An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service

NCT07296770 · TPS-Select · University of California, San Francisco

Closed to entry

Status

Not accepting participants

Phase 3

Phase

474

Target enrolment

Study sites

1 US states

What it is testing

Summary

The goal of this clinical trial is to learn whether a pain-management program called a Transitional Pain Service can help prevent long-term pain and reduce opioid needs after surgery in adult surgical patients who may be at higher risk for developing persistent pain. The main questions this trial aims to answer are: 1) Does the Transitional Pain Service help high-risk surgical patients manage pain better after surgery? 2) Can a computer tool (an algorithm) improve screening of patients for long-lasting pain after surgery? The investigators will compare patients who continue with their usual care to patients who receive support from the Transitional Pain Service to see if the program leads to better pain control and lower opioid use. Participants will share information about their pain levels and the pain-relief treatments they are using before and after surgery so researchers can better understand how the program affects recovery. Patients assigned to the Transitional Pain Service will also be offered additional coordinated support before and after their surgery to help optimize their pain control and overall recovery.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

Presence of Chronic Post-Surgical Pain
Measured over 90 days after date of surgery

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years

Ages

All

Sex

Not accepted

Healthy volunteers

Patients may take part in this study if they: * Are 18 years or older * Are having a planned (elective) surgery at UCSF * Are identified as higher risk for chronic pain after surgery by a computer model * Agree to join the study and sign consent Patients cannot take part if they: * Have too much missing information in their medical record (more than 75%) * Have a surgery scheduled less than 21 days away * Have serious memory or thinking problems that make participation difficult * Are in another clinical study that would interfere with this one * Do not live in California * Choose not to participate or sign consent * Have severe depression with suicidal thoughts that requires urgent care * Are pregnant or breastfeeding A patient who has already joined may be removed from the study if they: * Cannot complete most of the scheduled follow-up phone calls or pre-surgery recommendations (up to 6 months after discharge) * Pass away between the surgery booking date and 6 months after leaving the hospital * Become pregnant in the 6 months after discharge Patients may remain enrolled but their data may not be used in the main study results if they experience: * A long-lasting infection after surgery * Hardware problems related to their surgery (for example, issues with implanted devices) * A major injury or life event that affects their pain levels, such as a significant fall or an emergency surgery * Difficulty completing the planned follow-up phone calls up to 6 months after discharge

Where

1 study site

Facility	City	Region	Country
UCSF Hospitals	San Francisco	California	United States

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record. The registry also holds the most current version of everything above.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT07296770 on ClinicalTrials.gov →

Last updated in the registry 2026-10-09. Registry records change; this page reflects the data build of 2026-10-30.

Where this trial sits

Substance

Ketamine

Recruiting in

California118

All 4 trials from University of California, San Francisco →