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CompletedNot applicable

Comparison of Propofol and Ketofol as Induction Agents for Electroconvulsive Therapy

NCT07273851 · Fauji Foundation Hospital

Closed to entry
Status
Not accepting participants
Not applicable
Phase
80
Target enrolment
1
Study sites
Outside the US

What it is testing

Summary

This randomized controlled trial will compare two anesthetic agents, propofol and ketofol (a combination of propofol and ketamine), in patients undergoing electroconvulsive therapy (ECT). Propofol is commonly used but may lower blood pressure, while ketofol may help maintain more stable cardiovascular function. The study will evaluate changes in systolic blood pressure following ECT when either propofol or ketofol is used for anesthesia induction. A total of 80 adult patients will be enrolled and randomly assigned to one of the two treatment groups. Findings may guide anesthesiologists in selecting the safest and most effective induction agent for ECT.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • Mean Systolic Blood Pressure 20 Minutes After Electroconvulsive Therapy

    Measured over 20 minutes after seizure stimulus during the index ECT session

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years to 65 Years
Ages
All
Sex
Not accepted
Healthy volunteers
Inclusion Criteria: * Adults aged 18-65 years Both genders ASA physical status I-II Scheduled for electroconvulsive therapy Exclusion Criteria: * History of chronic opioid therapy Pregnancy Known allergy or hypersensitivity to propofol or ketamine History of cardiovascular disease History of renal disease

Where

1 study site

FacilityCityRegionCountry
Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi, PakistanRawalpindi—Pakistan

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT07273851 on ClinicalTrials.gov →

Last updated in the registry 2025-12-12. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits

Substance