Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence

Inclusion Criteria: * Individuals of all sexes, gender identities, and ethnicities * Ages 19 to 65 years at the time of screening * At least 6 months since last IPV incident * A score of 1 on the Composite Abuse Scale with repetition of abusive events * Minimum PCL-5 score of ≥ 33 * Limited lifetime use of serotonergic hallucinogens * Ability to read/write English Exclusion Criteria: * Severe or moderate substance use disorder other than nicotine in past 6 months * Lifetime diagnosis of schizophrenia or bipolar disorders (or first or second-degree relative) * Active suicidal ideation or serious attempt within the past 1 year. * Current pregnancy or nursing, trying to become pregnant * Any notable abnormality on ECG or routine medical blood laboratory test * Insulin-dependent diabetes; if taking oral hypoglycemic agent, then no history of hypoglycemia * Epilepsy with a history of seizures * Current or recent (within 12 weeks) participation in a clinical trial * Cognitive impairment (SLUMS score \<20) * Suffered a moderate/severe TBI at least once in lifetime * Suffered a mild TBI within the last 6 months * Any other circumstances that, in the opinion of the investigators, compromises participant safety * Not compelled to enter treatment to avoid legal consequences