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CompletedNot applicableResults posted

Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia

NCT02761330 · RCC2 · Washington University School of Medicine

Closed to entry
Status
Not accepting participants
Not applicable
Phase
17
Target enrolment
1
Study sites
1 US states

What it is testing

Summary

This study is geared toward characterizing the recovery of brain activity and cognitive function following treatments of electroconvulsive therapy and ketamine general anesthesia.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • Change in Cognitive Function During Recovery: Rate of Recovery

    Measured over 0, 30, 60, 90, 120 minutes following return of consciousness, assessed on treatment days 1-6.

  • Change in Cognitive Function During Recovery: Initial Decrement

    Measured over 0, 30, 60, 90, 120 minutes following return of consciousness, assessed on treatment days 1-6.

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years to 60 Years
Ages
All
Sex
Not accepted
Healthy volunteers
Inclusion Criteria: * Treatment resistant depression requiring outpatient ECT * Planned right unilateral ECT stimulation * English speaking * Able to provide written informed consent Exclusion Criteria: * Known brain lesion or neurological illness that causes cognitive impairment * Schizophrenia * Schizoaffective disorder * Blindness or deafness or motor impediments that may impair performance for cognitive testing battery * Inadequate ECT seizure duration with etomidate

Where

1 study site

FacilityCityRegionCountry
Washington University School of MedicineSt LouisMissouriUnited States

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT02761330 on ClinicalTrials.gov →

Last updated in the registry 2021-06-28. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits