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Ketamine Anesthesia in Electroconvulsive Therapy

NCT01367119 · Mayo Clinic

Closed to entry
Status
Not accepting participants
Not applicable
Phase
38
Target enrolment
1
Study sites
1 US states

What it is testing

Summary

Does the use of ketamine as the anesthetic medication in electroconvulsive therapy (ECT) accelerate the antidepressant effect of ECT? The study hypothesis was that depressed subjects receiving ECT with ketamine as the anesthetic agent would demonstrate a faster rate of improvement, defined as lower depression ratings after the second ECT than depressed patients receiving ECT with the usual anesthetic agent.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • Mean Depression Rating Using the Hospital Anxiety and Depression Scale (HADS)

    Measured over Baseline and after every second treatment for 7 treatments

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years
Ages
All
Sex
Not accepted
Healthy volunteers
Inclusion criteria: * Diagnosis of depression, either unipolar or bipolar * Subjects receiving ECT at the Mayo Clinic Exclusion criteria: * Subjects not giving their own consent to ECT * Subjects with schizophrenia, schizoaffective disorder, or dementia * Subjects diagnosed with a major neurological disorder such as epilepsy, Parkinson disease, multiple sclerosis, or a neurodegenerative dementia.

Where

1 study site

FacilityCityRegionCountry
Mayo Clinic in RochesterRochesterMinnesotaUnited States

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT01367119 on ClinicalTrials.gov →

Last updated in the registry 2013-08-08. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits

Substance

Indication

Recruiting in

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