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CompletedPhase 4

The Use of Ketamine as an Anaesthetic During Electroconvulsive Therapy

NCT01306760 · KANECT · University of Aberdeen

Closed to entry
Status
Not accepting participants
Phase 4
Phase
40
Target enrolment
1
Study sites
Outside the US

What it is testing

Summary

The main aim of this research is to ascertain whether Ketamine would be a more effective anaesthetic for Electroconvulsive Therapy (ECT) than the standard anaesthetic. In doing so the investigators aim to examine the effect of ketamine on ratings of depressive symptoms, the number of required ECT treatments, and the effect of this anaesthetic on memory.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • Change in depressive symptoms

    Measured over After 4th treatment

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years to 65 Years
Ages
All
Sex
Not accepted
Healthy volunteers
Inclusion Criteria: * between the ages of 18 and 65 years old * diagnosed with depression and being referred for ECT * American Society of Anesthesiologists (ASA) score of 1 or 2 * patient receiving ECT on an informal basis (i.e. consenting to treatment and able to give informed consent) Exclusion Criteria: * pre-existing neurological disease or cognitive impairment * co-morbid psychiatric diagnoses * pre-existing hypertension * severe respiratory tract disease * major cardiovascular disease * pacemakers * cerebrovascular disorder or malformation * intracranial mass lesions * seizure disorder * intracranial electrode or clips * intra-ocular pathology * endocrine or metabolic disease * severe hematologic disease * severe fracture * not able to give consent * pregnancy

Where

1 study site

FacilityCityRegionCountry
Royal Cornhill Hospital, NHS GrampianAberdeen—United Kingdom

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT01306760 on ClinicalTrials.gov →

Last updated in the registry 2016-09-08. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits

Substance

Indication