Industry sponsor

Janssen-Cilag International NV

2 registered trials on this registry. An industry sponsor is running trials with a view to approval and sale.

Registered trials

Recruiting

In Phase 3

With results posted

Working on

Substances

Trials

Trial	Status	Phase	Substance	Sites
A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive DisorderNCT04338321 · Janssen-Cilag International NV	Completed	Phase 3	ketamine	171
A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant DepressionNCT03852160 · Janssen-Cilag International NV	Withdrawn	Phase 3	ketamine	—

Sponsor attribution is the lead sponsor recorded on ClinicalTrials.gov API v2. Collaborators are not counted here. Data build 2026-08-25.