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Indication

Opioid Use

18 registered trials testing Ketamine for this indication, 4 recruiting now.

18
Registered trials
4
Recruiting
1
In Phase 3

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Trials

All 18 trials for Opioid Use

TrialStatusPhaseSubstanceSites
Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm RepairNCT04894864 · University of CreteRecruitingPhase 4ketamine1
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma PatientsNCT06903819 · Texas Tech University Health Sciences CenterRecruitingPhase 4ketamine2
Analgesic Efficacy of Intravenous Ketamine as a Continuous Infusion vs PCA in the Management of Acute Postoperative Pain in Major Orthopedic Surgery.NCT06774274 · Universidad de AntioquiaRecruitingPhase 4ketamine1
Dexmedetomidine and Ketamine in VATS SurgeryNCT03596424 · Ciusss de L'Est de l'Île de MontréalRecruitingNot applicableketamine1
The Impact of Perioperative Ketamine Infusion on Surgical RecoveryNCT04625283 · Vanderbilt University Medical CenterCompletedPhase 4ketamine1
Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the EDNCT05422001 · University of AarhusTerminatedPhase 4ketamine1
Ketamine for Acute Pain Management After TraumaNCT04129086 · The University of Texas Health Science Center, HoustonCompletedPhase 4ketamine1
Opioid Free vs Opioid Based Anesthesia for Laparoscopic Sleeve GastrectomyNCT04260659 · Medical University of WarsawCompletedPhase 4ketamine1
Ketamine Versus Fentanyl for Surgical AbortionsNCT04871425 · University of WashingtonCompletedPhase 4ketamine1
Opioid-Free Pain Control Regimen Following Robotic Radical ProstatectomyNCT05597878 · Wake Forest University Health SciencesTerminatedPhase 2 / Phase 3ketamine1
Ketamine to Improve Recovery After Cesarean Delivery - Part 1NCT04037085 · Grace Lim, MD, MSCompletedPhase 2ketamine2
Ketamine Administration for Postoperative Pain Management in Patients Undergoing Knee ArthroplastyNCT07059429 · State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of RussiaCompletedNot applicableketamine1
Outcome of Multimodal Anesthesia BernNCT06985069 · Insel Gruppe AG, University Hospital BernCompletedNot applicableketamine1
Opioid-based Versus Opioid-free Endotracheal IntubationNCT06464393 · Aretaieion University HospitalCompletedNot applicableketamine1
The Postoperative Lidocaine and Ketamine Effects on Morphine Requirement in Bariatric SurgeryNCT05591105 · Tiva GroupCompletedN/Aketamine1
Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French CLCCNCT04459234 · Centre Leon BerardCompletedN/Aketamine12
Opioid Free Anesthesia and Major Spine SurgeryNCT03417193 · Lebanese American UniversityCompletedNot applicableketamine1
Opioid Free Anesthesia in Bariatric SurgeryNCT03507634 · Lebanese American UniversityCompletedNot applicableketamine1

Records from ClinicalTrials.gov API v2, data build 2026-08-25. Indications are the sponsors’ own words. LSD.com reports registered clinical research. It is not medical advice, it is not a recommendation to take any substance, and trial listings are not endorsements. Talk to a clinician.