Not yet recruitingEarly Phase 1

Ketamine and Lidocaine Infusion in Refractory Chronic Migraine

NCT06935552 · Assiut University

Closed to entry

Status

Not accepting participants

Early Phase 1

Phase

Target enrolment

—

Study sites

What it is testing

Summary

Ketamine and lidocaine infusion for refractory chronic migraine: Comparative Study

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

Changes in pain scale using Numeric rating scale
Measured over From enrollment to the end of treatment at 6 weeks
Changes in pain scale using Migraine disability assessment
Measured over From enrollment to the end of treatment at 6 weeks

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years to 60 Years

Ages

All

Sex

Not accepted

Healthy volunteers

Inclusion Criteria: * All participants must fulfill the following inclusion criteria 1. medically stable outpatients with confirmed diagnosis of refractory chronic migraine according to American Headache society 2. Are reliable and willing to make themselves available for the duration of the study and are willing to follow up. 3. Men or women older than 18years of age. 4. clear written informed consent from each participant in the trial. 5. Adult patients with refractory migraine or refractory chronic migraine defined according to the American headache society Exclusion Criteria: 1. Pregnancy, active psychosis, liver disease, uncontrolled cardiac disease or cardiac rhythm abnormalities 2. presence of clinically significant medical or psychiatric condition that may increase the risk associated with the study 3. participation in any other type of medical research that may interfere with the interpretation of the study. 4. patients with hemocoagulation disorders, local infection or those who refused to consent

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT06935552 on ClinicalTrials.gov →

Last updated in the registry 2025-04-20. Registry records change; this page reflects the data build of 2026-08-25.

Where this trial sits

Substance

Ketamine

All 2 trials from Assiut University →