Unknown statusNot applicable

Effect of eHealth on AB Use of Children With Acute, Uncomplicated URTIs

NCT06140446 · Max Nieuwdorp

Closed to entry

Status

Not accepting participants

Not applicable

Phase

411

Target enrolment

Study sites

Outside the US

What it is testing

Summary

The goal of this clinical trial is to test the effectiveness of two self-care eHealth applications in parents of children with uncomplicated upper respiratory tract infections (URTIs). The main question it aims to answer is: • What is the effect of a self-management FeverApp and a self-care herbal medicine decision making tool (DMT) on reducing antibiotic use for acute, uncomplicated URTIs, among children in Dutch general practice? Participants will: * Complete an online questionnaire at baseline * Use a self-care eHealth application for ten days (in the intervention groups) * Report symptom severity of the URTI of their child online at day 2, 5 an 7 * Complete an online follow-up questionnaire at day 10 * Collect two stool samples of their child at baseline and at day 10 Researchers will compare three groups to see if the Apps have an effect on recovery time and complications from URTIs, AB use, frequency of GP visits, and diversity of the gut microbiome: * Parents that will use an evidence based fever app additional to standard advices of their GP * Parents that will use an evidence based herbal medicine DMT additional to standard advices of their GP * A control group of parents who will receive just standard advices from their GP,

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

Antibiotic use (yes/no)
Measured over Self-reported10 days after inclusion in the study

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

3 Months to 12 Years

Ages

All

Sex

Not accepted

Healthy volunteers

Inclusion Criteria: * Having a child aged 0-12 years old * Master the Dutch language * Having called the GP for their child aged 0-12 years having: * Fever (≥38 °C) AND * At least one of the following symptoms: * Acute cough * Sore throat * Earache/runny ear * Nasal congestion/runny nose * Headache * Being screened by a triage specialist (GP practice assistant) and not being indicated for a GP/NP/PA visit * Not being included in the trial before Exclusion Criteria: * The current URTI complaints of the child already exist longer than 2 weeks * The child who has a URTI * is younger than 3 months old * has asthma or another chronic or severe illness * has a history of pneumonia * has a history of complications or hospitalization from a previous URTI * has Down Syndrome * has a less functioning immune system * The parent being very worried

Where

1 study site

Facility	City	Region	Country
Amsterdam UMC location AMC	Amsterdam	—	Netherlands

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

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NCT06140446 on ClinicalTrials.gov →

Last updated in the registry 2023-11-21. Registry records change; this page reflects the data build of 2026-08-25.

Where this trial sits

Substance