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CompletedPhase 4

Impact of Ketamine On Depressive Symptoms In Patients Undergoing Lumbo-peritoneal Shunt Insertion

NCT06060210 · Benha University

Closed to entry
Status
Not accepting participants
Phase 4
Phase
110
Target enrolment
1
Study sites
Outside the US

What it is testing

Summary

Postoperative depression is a perioperative psychological complication that severely affects patient recovery and quality of life. In extreme cases, it may lead to suicidal behavior. Postoperative depression can be seen in various surgical operations . High rates of anxiety and depression have been reported in cohorts of patients with IIH, though it is not clear whether there is any direct relationship. Worse outcomes in terms of disability level and symptom resolution have been observed in IIH patients who have a known co-existing psychiatric illness compared to those who do not .

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • the rate of response to treating postoperative depression

    Measured over at 3 postoperative days

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

20 Years to 44 Years
Ages
All
Sex
Accepted
Healthy volunteers
Inclusion Criteria: * patients of both sex * with an age range from 20 to 44 years old * having moderate to severe depressive symptoms * an expected hospital stay of no less than 7 days Exclusion Criteria: * history of epilepsy * major depressive disorder patients * drug abuse * history of allergy to the research drug * heart rate \> 120 beats per minute * systolic blood pressure \> 180 mmHg * heart failure * renal or liver dysfunction * patients who cannot cooperate to complete psychiatric assessments * pregnant or breast-feeding women * patients who refuse to sign informed consent.

Where

1 study site

FacilityCityRegionCountry
Banha faculity of medicineBanhāElqalyoubeaEgypt

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT06060210 on ClinicalTrials.gov →

Last updated in the registry 2026-01-08. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits

Substance