RecruitingN/A

Ketamine Enhances Analgesia and Mood in Chronic Pain Patients

NCT05985811 · Salem Anaesthesia Pain Clinic

Recruiting

Status

Accepting participants

Not applicable

Phase

500

Target enrolment

Study sites

Outside the US

What it is testing

Summary

Most chronic pain patients have mood disorders. The mood disorders may improve with better analgesia produced by Ketamine injections. A prospective study of patients undergoing interventional pain therapy using Ketamine injections. Pre-injection and post-injection patient data is collected. Pain is measured using numeric pain rating scale, and change in pain score by 2-points is considered significant. Sleep is measured using Likert sleep scale, and change in sleep score by 2-points is considered significant. Anxiety is measured using general anxiety disorder (GAD-7) scale, and change in anxiety score by 4-points is considered significant. Depression is measured using patient health questionnaire (PHQ-9), and change in depression score by 5-points is considered significant.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

Pain score, objective measurement using the validated Numeric Pain Rating scale
Measured over 12 weeks

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

20 Years to 99 Years

Ages

All

Sex

Accepted

Healthy volunteers

Inclusion Criteria: * adult chronic pain patients * associated mood disorder * good treatment compliance * associated chronic insomnia * regular ketamine pain therapy injection * consent for clinical record quality assurance review Exclusion Criteria: * severe cognitive disorder * inability to provide consent * major neuropsychiatric disorder * cannabis use * stimulant use * substance abuse * poor treatment compliance * lack of ketamine pain therapy injection

Where

1 study site

Facility	City	Region	Country
Salem Anaesthesia Pain Clinic	Surrey	British Columbia	Canada

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

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NCT05985811 on ClinicalTrials.gov →

Last updated in the registry 2025-01-27. Registry records change; this page reflects the data build of 2026-08-25.

Where this trial sits

Substance

Ketamine