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MIH and Hypersensitivity in Children

NCT05705037 · Università degli Studi di Brescia

Closed to entry
Status
Not accepting participants
Not applicable
Phase
39
Target enrolment
1
Study sites
Outside the US

What it is testing

Summary

The aim of this study was to evaluate the efficacy of the association of casein phosphopeptide plus amorphous calcium phosphate (CPP-ACPF) mousse and photo-bio-modulation therapy (PMBT) (diode laser, RAFFAELLO 980 BIO - Dental Medical Technologies - DMT S.r.l.) in the treatment of dental hypersensitivity (DH) in children with Molar Incisor Hypomineralization (MIH) . Children aged 6-14 years with hypersensitive teeth were randomized into 3 groups. Group A received the application of CPP-ACPF mousse (GC MI Paste®) and sham light therapy; group B got the application of placebo mousse (Elmex Junior®) and PMBT; group C received both CPP-ACPF mousse and PMBT.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • Treatment of dental hypersensitivity (DH)

    Measured over 12 months

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

6 Years to 14 Years
Ages
All
Sex
Accepted
Healthy volunteers
Inclusion Criteria: * children 6-14 years old * having at least one MIH-affected tooth and MIH-associated hypersensitivity. Exclusion Criteria: * allergy to milk proteins * chronic diseases, * carious lesions on the sensitive teeth * restorations on the sensitive teeth * other enamel defects (fluorosis, amelogenesis/dentinogenesis imperfecta…) * presence of orthodontic appliance * recent anti-inflammatory or cortisone therapies * recent desensitizing treatments.

Where

1 study site

FacilityCityRegionCountry
Dental ClinicBrescia—Italy

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT05705037 on ClinicalTrials.gov →

Last updated in the registry 2023-01-30. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits

Substance