Skip to content
CompletedNot applicable

Cognitive Dysfunction After Cataract Surgery

NCT04730596 · Tanta University

Closed to entry
Status
Not accepting participants
Not applicable
Phase
90
Target enrolment
1
Study sites
Outside the US

What it is testing

Summary

* Cataract surgery is commonly performed in elderly patients who are at high risk for developing postoperative cognitive dysfunction. Most cataract surgeries are performed under peribulbar or retrobulbar anesthesia, however, most of the patients require sedation to relieve the perioperative anxiety and induce amnesia. So, many sedative agents can be used especially benzodiazepines which may increase the risk of developing postoperative cognitive dysfunction. * Ketamine can be used as a sedative and analgesic agent in a dose of 0.25 -0.5 mg/kg with certain studies suggesting that it may decrease the risk of postoperative cognitive dysfunction. Similarly, dexmedetomidine can be used as a sedative and analgesic agent with the possibility of decreasing the incidence of postoperative cognitive dysfunction. * this controlled study will compare the effect of ketamine or dexmedetomidine on the POCD of patients undergoing cataract surgery.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • The postoperative cognitive function

    Measured over Within the first 3 days after surgery

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

65 Years to 85 Years
Ages
All
Sex
Not accepted
Healthy volunteers
Inclusion Criteria: * Patients aged more than 65 years presented for cataract surgery under peribulbar anesthesia. Exclusion Criteria: * Patients with a history of psychological disorders as psychosis, schizophrenia, nephropathy. * Patients with uncontrolled medical conditions as D.M and hypertension. * Known allergy to the used medications * patients with hepatic, renal, or heart failure * Patients receiving anti-psychotic or anti-depressant medications.

Where

1 study site

FacilityCityRegionCountry
Faculty of MedicineTantaAlgharbia GovernateEgypt

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT04730596 on ClinicalTrials.gov →

Last updated in the registry 2021-04-20. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits