Skip to content
lsd.com
CompletedPhase 1 / Phase 2Results posted

The Effects of Sedatives on Tobacco Use Disorder

NCT03813121 · SED-TUD · Wake Forest University Health Sciences

Closed to entry
Status
Not accepting participants
Phase 1 / Phase 2
Phase
10
Target enrolment
1
Study sites
1 US states

What it is testing

Summary

This proposal will obtain preliminary data on the effect of a single sub-anesthetic dose of a sedative on cigarette craving and smoking behavior as well as measuring tolerability and acceptability.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • Side Effects

    Measured over about 1 week post infusion

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years to 55 Years
Ages
All
Sex
Accepted
Healthy volunteers
Inclusion Criteria: * smoke at least 5 cigarettes per day * smoked at least 2 years * negative urine drug screen for psychoactive drugs and negative breath alcohol concentration * live in Little Rock AR or surrounding area Exclusion Criteria: * unstable or stable medical condition that would interact with study medication or participation * serious head trauma or neurological disorder * hypertension, abnormal ECG or metabolic blood results * meet criteria for psychosis, schizophrenia, major depressive disorder, or bipolar disorder * use of psychoactive drugs or medications * BMI \> 40 * among women, pregnancy or breastfeeding

Where

1 study site

FacilityCityRegionCountry
University of Arkansas for Medical SciencesLittle RockArkansasUnited States

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT03813121 on ClinicalTrials.gov →

Last updated in the registry 2022-10-06. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits

Substance

Recruiting in

All 3 trials from Wake Forest University Health Sciences →