Skip to content
lsd.com
CompletedNot applicable

Effect of Ketamine in Depressive Symptoms of Elderly Patients With Visual Impairment.

NCT03473431 · Instituto Mexicano del Seguro Social

Closed to entry
Status
Not accepting participants
Not applicable
Phase
90
Target enrolment
1
Study sites
Outside the US

What it is testing

Summary

the prevalence of depression in elderly is from 4 to 30% and is associated with a lower quality of life mayor medical comorbidity, and increased mortality. Although there are various treatments for depression in the elderly, the study of interventions in resistant depression is limited and there are few reports of the efficacy and safety profile of alternative interventions such as ketamine in the elderly. The final objective of the present study is to report the effects of a single infusion of ketamine on the depressive symptoms in patients undergoing ophthalmologic surgery

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

  • Depressive symptoms

    Measured over two hours and 24 hours after the ketamine infusion

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

60 Years
Ages
All
Sex
Accepted
Healthy volunteers
Inclusion Criteria: * Men and women aged 60 years or older who due to the severity of visual disability required to be operated on for eye surgery using retrobulbar block * Intraocular pressure \<20 mm Hg and * ASA functional capacity from I to III Exclusion Criteria: * Previous antidepressants medications * Cognitive impairment was found according to the Short Portable Mental Status Questionnaire (SPMSQ) assessment * In case of a history of psychosis, schizophrenia, nephropathy * They had a history of difficulties to control arterial blood pressure, uncontrolled hepatic disorders or had a history of adverse response to ketamine according clinical records

Where

1 study site

FacilityCityRegionCountry
Centro Medico Nacional Siglo XXI. UMAE Hospital de EspecialidadesMexico CityMexico CityMexico

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT03473431 on ClinicalTrials.gov →

Last updated in the registry 2019-02-28. Registry records change; this page reflects the data build of 2026-08-25.

Related

Where this trial sits

Substance