CompletedNot applicableResults posted

Effects of MDMA on Emotional and Social Memories

NCT03050541 · University of Chicago

Closed to entry

Status

Not accepting participants

Not applicable

Phase

Target enrolment

—

Study sites

What it is testing

Summary

The purpose of this study is to examine the effects of MDMA on encoding and retrieval of emotional and social memories in healthy young adults. The study will explore the effects on memory retrieval when the drug is administered 1) before encoding, and 2) before retrieval.

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

What counts as success

Primary outcome measures

Probability of Accurately Recalling Visual Stimuli
Measured over 90 minutes into Session 2

A trial succeeds or fails on its primary outcome, declared in advance. Everything else it reports is secondary by definition.

Who can take part

Eligibility, as published

18 Years to 40 Years

Ages

All

Sex

Accepted

Healthy volunteers

Inclusion Criteria: * Normal healthy males and females, aged 18-40 years. Exclusion Criteria: 1. any current medical condition requiring medication or abnormal electrocardiogram 2. current or past medical condition considered to be a contraindication for the study conditions 3. any current Axis I psychiatric disorder (APA, 1994) including Substance Use Disorder, or Anxiety Disorder or Major Depression in the past year, any history of psychosis 4. less than high school education 5. lack of fluency in English 6. night shift work 7. pregnancy, lactation, or plans to become pregnant 8. use of hormonal contraception

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT03050541 on ClinicalTrials.gov →

Last updated in the registry 2018-06-29. Registry records change; this page reflects the data build of 2026-08-25.

Where this trial sits

Substance

MDMA

All 12 trials from University of Chicago →