CompletedN/A

The NeXT Study; The Netherlands XTC Toxicity Study

NCT00235768 · UMC Utrecht

Closed to entry

Status

Not accepting participants

Not applicable

Phase

225

Target enrolment

Study sites

Outside the US

What it is testing

Summary

The purpose of this study is to investigate the possible neurotoxic effects of the party-drug Ecstasy (MDMA)on brain and brain function in humans. Main research questions concern the causality, course and clinical relevance of the neurotoxicity of ecstasy

Summary as written by the trial’s own sponsor and published on ClinicalTrials.gov API v2. It is the sponsor’s description, reproduced unedited, not an assessment by this site.

Who can take part

Eligibility, as published

18 Years to 35 Years

Ages

All

Sex

Accepted

Healthy volunteers

Inclusion Criteria: * between 18 - 35 years of age Exclusion Criteria: * severe medical or neuropsychiatric illness * use of prescribed psychotropic medications such as SSRI's * use of intravenous drugs * pregnancy * contra-indications for MRI investigation

Where

3 study sites

Facility	City	Region	Country
Bonger Institute of Criminology	Amsterdam	North Holland	Netherlands
Academic Medical Center Amsterdam	Amsterdam	North Holland	Netherlands
University Medical Center Utrecht	Utrecht	Utrecht	Netherlands

On the registry

Contact the trial directly

This site does not enrol anyone and is not involved in this trial. To ask about taking part, use the sponsor’s own contact details on the official registry record, which is also where the most current version of everything above lives.

Before you do, the preparation checklist lists what a site will ask you on a first call and what is worth asking them. It is free and collects nothing.

NCT00235768 on ClinicalTrials.gov →

Last updated in the registry 2005-10-10. Registry records change; this page reflects the data build of 2026-08-25.

Where this trial sits

Substance

MDMA