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Academic or other sponsor

National Institute of Mental Health (NIMH)

7 registered trials on this registry, 4 recruiting now. An academic sponsor is usually answering a scientific question rather than seeking approval, which changes what its trials are designed to show.

7
Registered trials
4
Recruiting
0
In Phase 3
3
With results posted

Working on

Substances

Trials

All 7 trials

TrialStatusPhaseSubstanceSites
Neurobiology of SuicideNCT02543983 · National Institute of Mental Health (NIMH)RecruitingPhase 2ketamine1
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant DepressionNCT06511908 · National Institute of Mental Health (NIMH)RecruitingPhase 2ketamine1
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive DisorderNCT03065335 · National Institute of Mental Health (NIMH)RecruitingPhase 1ketamine1
Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major DepressionNCT03973268 · National Institute of Mental Health (NIMH)RecruitingPhase 1ketamine1
Rapid Antidepressant Effects of Ketamine in Major DepressionNCT00088699 · National Institute of Mental Health (NIMH)CompletedPhase 1 / Phase 2ketamine1
Phase 1 Evaluation of (2R,6R)-HydroxynorketamineNCT04711005 · National Institute of Mental Health (NIMH)CompletedPhase 1ketamine1
[11C]-(R)-Rolipram to Measure cAMP Signaling Before and After KetamineNCT05522673 · National Institute of Mental Health (NIMH)TerminatedPhase 1ketamine1

Sponsor attribution is the lead sponsor recorded on ClinicalTrials.gov API v2. Collaborators are not counted here. Data build 2026-08-25.