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Indication

Bipolar Disorder

18 registered trials testing Ketamine for this indication, 3 recruiting now.

Sponsors register this under 2 different names, all collected here: Bipolar Disorder · Bipolar Disorder (BD)

18
Registered trials
3
Recruiting
2
In Phase 3

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Trials

All 18 trials for Bipolar Disorder

TrialStatusPhaseSubstanceSites
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)NCT07569198 · Joshua RosenblatRecruitingPhase 2ketamine1
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal EffectsNCT05786066 · Yale UniversityRecruitingPhase 2ketamine1
University of Iowa Interventional Psychiatry Service Patient RegistryNCT04480918 · Mark NiciuRecruitingN/Aketamine1
Treatment Study of Bipolar DepressionNCT00947791 · Icahn School of Medicine at Mount SinaiTerminatedPhase 4ketamine1
NMDA Antagonists in Bipolar DepressionNCT01833897 · New York State Psychiatric InstituteCompletedPhase 4ketamine1
Predictors of Intravenous Ketamine Response in TRDNCT05625555 · Abraham NunesActive, not recruitingPhase 3ketamine1
Intranasal Ketamine In the Treatment of Pediatric Bipolar DisorderNCT01504659 · Juvenile Bipolar Research FoundationTerminatedPhase 2 / Phase 3ketamine4
Ketamine for Treatment-Resistant Bipolar DisorderNCT05004896 · Joshua RosenblatCompletedPhase 2ketamine3
Maintenance Ketamine Infusions for Treatment-Resistant Bipolar DepressionNCT05339074 · Joshua RosenblatCompletedPhase 2ketamine3
The UTHealth Ketamine ProjectNCT02882711 · The University of Texas Health Science Center, HoustonTerminatedPhase 2ketamine1
Ketamine for Suicidality in Bipolar DepressionNCT01944293 · New York State Psychiatric InstituteCompletedPhase 1 / Phase 2ketamine1
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response, Pilot TrialNCT03367533 · Yale UniversityCompletedPhase 1ketamine1
Behavioural Activation Therapy and Esketamine for Resistant DepressionNCT06431386 · The Royal's Institute of Mental Health ResearchTerminatedNot applicableketamine1
Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar DepressionNCT05177146 · Centre for Addiction and Mental HealthCompletedNot applicableketamine1
Synaptic Imaging and Network Activity in Treatment Resistant DepressionNCT05870501 · King's College LondonCompletedNot applicableketamine1
Chart Review of Patients Undergoing Ketamine InfusionsNCT04209296 · Brain and Cognition Discovery FoundationCompletedN/Aketamine1
Naturalistic Study of Ketamine in the Treatment of DepressionNCT05249309 · Hospital de Clinicas de Porto AlegreUnknown statusN/Aketamine2
Open Study of the Neurobiological Effects of Intranasal Ketamine in Children and Adults With Bipolar DisorderNCT05209217 · Mclean HospitalUnknown statusN/Aketamine1

Records from ClinicalTrials.gov API v2, data build 2026-08-25. Indications are the sponsors’ own words. LSD.com reports registered clinical research. It is not medical advice, it is not a recommendation to take any substance, and trial listings are not endorsements. Talk to a clinician.